Botox a ground-breaking treatment for Erectile Dysfunction

DermaHealth
May 26, 2016 

Cairo, Egypt -  Two new Egyptian studies, conducted by Andrologists & Cosmetic Dermatologists in Cairo University,  confirm that botulinum toxin type A known as Botox or Dysport is an effective treatment for Men suffering from Impotence (Erectile Dysfunction), not responding to other forms of therapy.

Egyptian researchers at Cairo university completed 2 human and animal studies confirming that botulinum toxin type A, the active component of Botox is effective in the treatment of Erectile Dysfunction.

To understand how this works, Prof. Hussein Ghanem, Cairo University,  Assistant.Prof Amr  Abd El Raheem, and Dr. Islam Soliman explain that to obtain a full erection certain vascular events need to occur; the arteries dilate to increase the blood flow to the spongy tissues, the smooth muscles within the spongy tissues relaxes to accept the incoming blood, thus compressing the veins lying between these spaces to close the blood outflow from the penis.

The rational for these studies is that Botox, a powerful muscle relaxant, could relax these muscles for 3 to 6 months thus facilitating the erection process.

During research with 30 rats, Botox was found to increase the diameter of blood spaces in rats injected with botox compared to control rats.  In the human study of 24 patients, improvement in erections and penile blood flow were documented in the group of patients receiving botox versus the control group. Safety and effectiveness were documented in both studies Following these 2 research projects, Canadian researchers, one year later, confirmed improved sexual function in older rats injected with Botox.

Currently a large-scale study is being conducted in Cairo University in association with the Andrology International group to further confirm these findings.

More Information

1. European Society of Sexual Medicine (ESSM) 2016, Madrid
PS-08-016 Can intracavernosal botulinum toxin injection salvage vascular erectile dysfunction patients not responding to oral and intracavernous therapy? A pilot stud

Published in issue: May 2016
H. Ghanem, I. Soliman, M. AbdulHamid, R. Shamloul
Cairo University, Faculty of Medicine, Cairo, Egypt
The Journal of Sexual Medicine, Vol. 13, Issue 5, S116
http://www.jsm.jsexmed.org/article/S1743-6095(16)00447-1/pdf
2. International Society of Sexual Medicine (ISSM) Sep 2016, Beijing, China.
The effect of botulinum toxin on penile vascular parameters and clinical outcome in patients with severe ED: A pilot study.
Ghanem, H1; Fathy, I2; Abdel Raheem, A1; Shamloul, R2; Abdel Hamid, M1
Cairo University, Faculty of Medicine, Cairo, Egypt
http://www.wmsm.org/index.php?option=com_content&view=article&id=195&abstract_id=251
3. Sexual Medicine Society of North America (SMSNA) November 3-6, 2016, Scottsdale, Arizona
Safety and Effectiveness of Botulinum Toxin in the Treatment of Severe ED: A Pilot Study
G Ghanem, H1; Abdel Raheem, A1; Fathy, I1
Cairo University, Faculty of Medicine, Cairo, Egypt
http://smsna.org/V1/index.php?option=com_content&view=article&id=196&abstract_id=193
4. International Masters Course for Aging Skin (IMCAS 2017)
Intracavernosal injection of Botulinum Toxin Type A in the treatment of Vascular Erectile Dysfunction.
G Ghanem, H1; Abdel Raheem, A1; Fathy, I
Cairo University, Faculty of Medicine, Cairo, Egypt
http://www.imcas.com/en/academy/show/3085/pilot-study-male-genital-rehabilitation-using-botulinum-toxin-treatment-of-erectile-dysfunction